Evo 2
Arc InstituteEvo 2 is Arc Institute's autoregressive DNA language-model family for genome modeling and sequence design. It works at single-nucleotide resolution with contexts up to one million base pairs, spans multiple model sizes, and provides local inference, sequence generation, embeddings, and documented training and fine-tuning paths.
Verified 2026-09-10 via the Hugging Face model card and Arc Institute repository.
Openness
5 high confidence- weights
- open(Apache-2.0 ungated checkpoint)
- data
- open(OpenGenome2 raw FASTA and augmented JSONL released)
- code
- open(Savanna training framework and Evo 2 training guidance released)
- license
- Apache-2.0(OSI)
Evo 2 releases all three parts of the from-scratch stack: permissive weights, the OpenGenome2 training corpus, and the named open training framework.
- https://raw.githubusercontent.com/ArcInstitute/evo2/main/README.md recorded 2026-09-10
Links downloadable checkpoints, the OpenGenome2 raw and processed training data, and the open Savanna framework under its Training and Finetuning section.
- https://huggingface.co/api/models/arcinstitute/evo2_7b recorded 2026-09-10
license: apache-2.0; gated: false; private: false; evo2_7b.pt present.
Adoption
1 high confidence1,350 downloads in the trailing 30 days for the declared 7B checkpoint.
- https://huggingface.co/api/models/arcinstitute/evo2_7b recorded 2026-09-10
downloads: 1350; gated: false; private: false.
Capability
3 high confidenceTwo attributes. The multi-scale credit was withdrawn under ruling (e): 8K to one million bases is a longer window at the same single-nucleotide granularity, which is extent rather than a second scale, and it is the same reading that declines presto's 1-24 monthly timesteps and aifs's 13 pressure levels. Model-size variety is not an instrument.
- https://raw.githubusercontent.com/ArcInstitute/evo2/main/README.md recorded 2026-09-10
Documents training and fine-tuning, prompted DNA generation, and checkpoints spanning 8K, 262K, and one-million-base contexts.
Verified 2026-09-10